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Response to Treatment

Testicular tumors are divided into three groups, depending on how well the tumors are expected to respond to treatment. These groups include:
 
  • Good prognosis
  • Intermediate prognosis
  • Poor prognosis.
     
Good Prognosis
In order for a patient with nonseminoma to receive a good prognosis, all of the following must be true:
 
  • The tumor is found only in the testicle or in the retroperitoneum (area outside or behind the abdominal wall)
     
  • The tumor has not spread to organs other than the lungs
     
  • The levels of all the tumor markers are slightly above normal.
     
In order for a patient with seminoma to receive a good prognosis, all of the following must be true:
 
  • The tumor has not spread to organs other than the lungs
     
  • The level of alpha-fetoprotein (AFP) is normal.
     

Beta-human chorionic gonadotropin (β-hCG) and lactate dehydrogenase (LDH) may be at any level.

 

Intermediate Prognosis
In order for a patient with nonseminoma to receive an intermediate prognosis, all of the following must be true:
 
  • The tumor is found only in one testicle or in the retroperitoneum
     
  • The tumor has not spread to organs other than the lungs
     
  • The level of any one of the tumor markers is more than slightly above normal.
     
In order for a patient with seminoma to receive an intermediate prognosis, all of the following must be true:
 
  • The tumor has spread to organs other than the lungs
     
  • The level of alpha-fetoprotein (AFP) is normal.
     

Beta-human chorionic gonadotropin (β-hCG) and lactate dehydrogenase (LDH) may be at any level.

Written by/reviewed by:
Last reviewed by: Arthur Schoenstadt, MD
Last updated/reviewed:
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