An intentional overdose with temsirolimus is unlikely to occur, as this medication is administered by a healthcare provider in a healthcare setting. Nonetheless, it is important to seek immediate medical attention if you or someone else may have used too much of this or any other medication.
If you miss an appointment to receive your temsirolimus dose, contact your healthcare provider right away. He or she will schedule another appointment for you. It is important to try not to miss doses of this medication.
How Does Temsirolimus Work?
Protein kinases are enzymes found in the body that regulate cell function, including cell growth. Temsirolimus works by blocking the action of a specific protein kinase called the mammalian target of rapamycin (mTOR).
When mTOR is not functioning properly, as is the case in certain types of cancer, it causes cells to grow and multiply abnormally. This enzyme also promotes blood vessel growth into tumors, which supplies cancer cells with nutrients and energy, and gives them a way to spread to other areas of the body.
By blocking the action of mTOR, temsirolimus may slow down the growth of cancer and tumor cells. It also cuts off the blood supply to cancer cells, which may help slow down the spread of the cancer.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed October 4, 2011.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed October 4, 2011.
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