Cancer Home > Drug Interactions With Temsirolimus

Echinacea, cyclosporine, live vaccinations, and certain other drugs may cause negative interactions when combined with temsirolimus. Some of these reactions can increase the risk for potentially serious side effects or decrease the effectiveness of the medicines. Your healthcare provider may need to monitor you more closely if you are undergoing temsirolimus treatment, and adjust your dosage amounts as needed.

An Overview of Temsirolimus Interactions

Temsirolimus (Torisel®) may interact with several other medications. Some of the drugs that may react with temsirolimus include but are not limited to:
 
  • ACE inhibitors, such as:
 
 
 
 
  • CYP 3A4 inhibitor medications, such as:
 
 
 
 
  • Medications that "thin" the blood (such as anticoagulant and antiplatelet drugs), such as:
 
 
 
 
      • Alteplase (Activase®)
      • Reteplase (Retavase®)
      • Streptokinase (Streptase®)
      • Tenecteplase (TNKase®)
 
 

 

 
  • P-glycoprotein inhibitors, such as:

 

 
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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