Cancer Home > Panitumumab Side Effects

Although not every who receives panitumumab will experience problems, most people will develop some type of side effect. Panitumumab has been shown to cause potentially serious problems, such as severe skin reactions or swelling of the throat, which should be reported to your healthcare provider immediately. Some of the more commonly reported reactions to this drug include fatigue, abdominal (stomach) pain, and constipation.

An Introduction to Side Effects of Panitumumab

Just like any medicine, panitumumab (Vectibix®) can cause side effects. Not everyone who receives the medication will have problems. However, most people will experience some type of side effect during panitumumab treatment. Some side effects may be treated by your healthcare provider with other medicines.
(This article covers many, but not all, of the possible side effects with panitumumab. Your healthcare provider can discuss a more complete list with you.)

Serious Panitumumab Side Effects

Some side effects of panitumumab are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an allergic reaction or infusion reaction (a reaction that happens during or shortly after your dose), such as:
    • Rash
    • Hives
    • Swelling of the mouth, tongue, face, lips, or throat
    • Difficulty breathing
    • Fever
    • Chills
  • Lung problems, such as:
    • Wheezing
    • Breathing difficulty
    • Persistent cough
  • Severe or persistent skin reactions or increased redness or swelling of the skin
  • Signs of infection, such as:
    • Fever
    • Chills
    • Body aches
  • Eye irritation, swelling, or pain
  • Changes in vision
  • Diarrhea, particularly severe or prolonged diarrhea
  • Signs of dehydration, such as:
    • Decreased urination
    • Dry mouth or lips
    • Sunken eyes
  • Sores, blisters, pain, or swelling in the mouth.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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