Cancer Home > Panitumumab Side Effects
Common Side EffectsPanitumumab has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people who received panitumumab were carefully documented and compared to the side effects that occurred in a similar group of people who did not receive panitumumab. As a result, it was possible to see what side effects occurred and how often they appeared.
In these studies, the most common panitumumab side effects included:
- Skin reactions -- in up to 90 percent of people
- Low blood magnesium levels (hypomagnesemia) -- up to 38 percent
- Fatigue -- up to 26 percent
- Infections around the toenails and fingernails -- up to 25 percent
- Abdominal (stomach) pain -- up to 25 percent
- Nausea -- up to 23 percent
- Diarrhea -- up to 21 percent
- Constipation -- up to 21 percent
- Vomiting -- up to 19 percent.
Other common side effects, occurring in 3 percent to 15 percent of people, included but were not limited to:
- Eye problems, such as:
- Swelling of the arms, hands, legs, ankles, and feet
- Sores and inflammation of the mouth
- Problems with the toenails or fingernails
- Growth of hair and eyelashes
- Reactions to the infusion.
The majority of people in clinical trials experienced a skin reaction of some type, usually within the first two weeks of starting treatment. Reported reactions included:
- An acne-like rash
- Other rashes
- Peeling skin
- Cracking skin
- Dry skin.