Cancer Home > Panitumumab

What If I Overdose on This Medication?

An overdose with this medicine may cause severe skin reactions, diarrhea, and tiredness. Seek immediate medical attention if you or someone else may have overdosed on this medication.
(Click Vectibix Overdose for more information.)

What Should I Do If I Miss a Dose of Panitumumab?

It is important to keep your scheduled appointments to receive panitumumab. If you miss an appointment, contact your healthcare provider right away to reschedule.

How Does It Work?

Panitumumab works by binding to a certain receptor in the body called epidermal growth factor receptor (EGFR). EGFR is found on the surface of normal cells and some cancer cells.
Normally, certain proteins, such as epidermal growth factor, bind to EGFR and tell cells to grow. By binding to EGFR, panitumumab blocks these proteins from binding and slows down the growth of cancer cells. Panitumumab does not cure cancer.

Clinical Effects

In clinical trials, panitumumab was shown to extend the amount of time until colorectal cancer progressed (got worse). In one study, people who received panitumumab had approximately 36 more days without further disease progression than people who did receive panitumumab. However, the medication did not appear to improve cancer symptoms or help people live longer.

When and How to Receive This Medicine

Some general considerations to keep in mind during treatment with panitumumab include the following:
  • This medication comes as a liquid (solution) that is given as a slow injection into a vein (an intravenous, or IV, infusion) every 14 days.
  • It normally takes 60 to 90 minutes to receive each panitumumab dose. Your healthcare provider may need to slow down or temporarily stop your dose if you experience a reaction during the infusion (an infusion reaction).
  • The infusion will be given by a trained healthcare provider in a healthcare setting, such as a hospital or clinic.
  • For this drug to work properly, it must be used as prescribed. The medication will not work as well if you miss doses.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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