Cancer Home > Drug Interactions With Panitumumab
If your healthcare provider has prescribed panitumumab to treat colorectal cancer, it is important to tell him or her about all other medications, vitamins, and herbal supplements you are taking. Research has shown that combining panitumumab with bevacizumab, fluorouracil, or other chemotherapy drugs could lead to interactions like a quicker progression of the cancer, a shorter lifespan, and potentially serious side effects.
An Overview of Panitumumab InteractionsPanitumumab (Vectibix®) can potentially interact with a few other medications. The medications that can lead to reactions with panitumumab include other anti-cancer or chemotherapy medications, including but not limited to:
- Bevacizumab (Avastin®)
- Oxaliplatin (Eloxatin®)
- Irinotecan (Camptosar®)
- Fluorouracil (Adrucil®, Carac®, Efudex®, Fluoroplex®, also known as 5-FU).
More Detail on Drug Interactions With PanitumumabPanitumumab is approved for use as a single agent for the treatment of certain types of colorectal cancer. It should not be used in combination with other chemotherapy medications.
In a study of people who received panitumumab in addition to bevacizumab and other chemotherapy agents, people who received the combination treatment had a faster disease progression, shorter lifespan, and an increased risk for serious side effects, such as: