Cancer Home > Oxymorphone ER

How Does It Work?

Oxymorphone ER tablets are specially designed to release oxymorphone over an extended period of time. As a result, you can take oxymorphone ER just twice a day, rather than taking short-acting oxymorphone (Opana®) many times a day.
Oxymorphone is an opioid narcotic medication that is chemically related to morphine. It binds to opioid receptors throughout the body and produces numerous effects, including but not limited to:
  • Pain relief
  • Drowsiness
  • Slowing of the digestive tract
  • Cough suppression
  • Release of histamine (which often causes itching)
  • Unusual unpleasant feelings (dysphoria) or unusual pleasant feelings (euphoria)
  • Decreased breathing (slow or shallow breathing)
  • Certain changes in the circulatory system
  • Physical dependence.

Oxymorphone ER Abuse Potential

Oxymorphone ER contains oxymorphone, a drug that may be abused (see Opana ER Abuse). Make sure to keep this medication in a safe place, where it is unlikely to be stolen by others. Never let someone else take your medication, as it contains a high dose of oxymorphone that could easily result in death in someone who is not used to the medication.
Also, it is very dangerous to inject this medication, as it contains inactive ingredients that can be quite harmful when injected into the bloodstream. People who abuse oxymorphone ER and suddenly stop using it are likely to experience withdrawal symptoms (see Opana ER Withdrawal).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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