Cancer Home > Onsolis Dosage
Different factors will affect the amount of Onsolis you are prescribed, such as how you respond to the medication, other medical conditions you may have, and the type and severity of your pain. When using Onsolis, the initial dosage is one 200-mcg film for each breakthrough pain episode. If necessary, your healthcare provider can increase this. However, do not use more than four doses each day.
An Introduction to Dosing With OnsolisThe dose of Onsolis™ (fentanyl buccal soluble film) your healthcare provider recommends will vary, depending on a number of factors, including:
- The type and severity of your pain
- How you respond to the medication
- Other medications you are taking
- Other medical conditions you may have.
As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.
Initial Onsolis DosageThe initial Onsolis dose for treating breakthrough pain is one 200-mcg film, applied to the inside of the cheek. If this dosage does not adequately relieve pain, the amount will be slowly increased to one that effectively treats pain with minimal side effects. Normally, the dose is increased by 200 mcg at each breakthrough pain episode, until the pain is effectively relieved.
For example, if the initial 200-mcg Onsolis dosage does not adequately relieve pain, the next breakthrough pain episode is treated with 400 mcg (two 200-mcg films). If the 400-mcg amount does not adequately relieve pain, the following breakthrough pain episode is treated with 600 mcg (three 200-mcg films).
Dosage increases continue in this manner up to 800 mcg (four 200-mcg films). If the 800-mcg dose does not cause adequate pain relief and side effects are tolerable, the next breakthrough pain episode will be treated with one Onsolis 1200-mcg film.
You must wait at least two hours between doses of Onsolis. In addition, this medicine can only be used once for each breakthrough pain episode. Do not retreat an episode with Onsolis, even if the first dose did not work. Your healthcare provider may give you another pain medication to use as needed in the event Onsolis does not relieve your pain after 30 minutes.