Cancer Home > Nucynta ER Dosage

Your individual Nucynta ER dosage will depend on various factors, including the type and severity of your pain, other pain medications you have taken, and other medical conditions you may have. The range tends to fall between 50 mg and 250 mg every 12 hours. However, the maximum daily dose should not exceed 500 mg.

An Introduction to Dosing With Nucynta ER

The dose of Nucynta® ER (tapentadol ER) your healthcare provider recommends will vary, depending on a number of factors, including:
  • The type and severity of your pain
  • How you respond to the medication
  • Other medications you are taking
  • Other pain medications you have tried
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Nucynta ER Dosage for Pain

As with many opioid pain relievers, there is variation in the dosage of Nucynta ER that can be tolerated and that will effectively relieve pain. This variation can depend on several factors, such as the severity of pain and the person's past history of opioid use (people become tolerant to the effects of opioids over time). In general, typical Nucynta ER doses range from 50 mg to 250 mg every 12 hours.
In many cases, people need to take short-acting "rescue" painkillers in addition to Nucynta ER to help control "breakthrough" pain. Importantly, short-acting Nucynta or any medication that contains tramadol (such as Rybix™ ODT, Ryzolt®, Ultram®, Ultram® ER, or Ultracet®) should not be used in combination with Nucynta ER. A different type of medication that does not contain tapentadol or tramadol should be used for breakthrough pain.
If you have liver disease, your healthcare provider may recommend starting with a low dose, as you may not handle Nucynta ER as well as normal.
It is a common "off-label" practice for long-acting, twice-daily narcotics to be prescribed on a more frequent basis (typically every 8 hours, instead of every 12 hours) for people who find the medication does not last long enough. No matter how often this medication is taken, the maximum total daily dosage of Nucynta ER is 500 mg.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation




Related Channels

eMedTV Links
Copyright © 2006-2019 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.