Cancer Home > Nolvadex Warnings and Precautions

Understanding Nolvadex warnings and precautions can help ensure a safe treatment process. For example, the medication can cause serious side effects, such as stroke, blood clots, or uterine cancer. Potential liver problems are also possible, including cirrhosis, hepatitis, and liver cancer. Nolvadex warnings and precautions also extend to those who are allergic to any components used to make the drug.

Nolvadex: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Nolvadex® (tamoxifen citrate) if you have:
  • Unexplained vaginal bleeding
  • A history of blood clots or stroke
  • Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Nolvadex Warnings and Precautions

Warnings and precautions to be aware of prior to taking Nolvadex include the following:
  • The medication can cause serious side effects, including blood clots, strokes, or uterine cancer. For some women, the risks of using Nolvadex to prevent breast cancer may outweigh any possible benefits. Be sure to talk to your healthcare provider about the benefits and risks of using the drug in your particular situation.
  • Nolvadex can cause high calcium levels in the body if given to people with bone metastases (spreading of the cancer to bone). If your calcium levels are extremely high, your healthcare provider may recommend that you stop taking the medication.
  • Nolvadex can increase the risk of uterine cancer. If you are taking the drug (or have taken it in the past), tell your healthcare provider right away if you have signs of uterine cancer, such as:
    • Changes in your menstrual period
    • Abnormal vaginal bleeding
    • Changes in vaginal discharge
    • Pelvic pain or pressure.
  • The medication may also increase the risk of non-cancerous uterine or ovary problems, such as uterine fibroids, endometriosis, or ovarian cysts.
  • Nolvadex can increase the risk of blood clots and strokes. If you have had a blood clot or stroke in the past, Nolvadex may not be the best choice for you.
  • There have been reports of liver problems in people taking Nolvadex. These problems include liver cancer, cirrhosis, and hepatitis. If you already have liver problems, talk to your healthcare provider before taking the drug.
  • Nolvadex can cause eye problems, including cataracts, vision changes, and other problems. Let your healthcare provider know if you notice any changes in your eyes or vision while taking the drug.
  • Nolvadex can interact with other medications (see Nolvadex Drug Interactions).
  • Nolvadex is considered a pregnancy Category D medication. This means that it is likely to cause harm to a fetus during pregnancy. Talk to your healthcare provider about the risks and benefits of taking the drug while pregnant (see Tamoxifen and Pregnancy).
  • It is not known if the medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking it (see Tamoxifen and Breastfeeding).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation




Related Channels

eMedTV Links
Copyright © 2006-2020 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.