Cancer Home > Myleran Drug Interactions

Metronidazole may increase blood levels of Myleran, which could increase your risk for Myleran side effects. It is generally advised that these medicines not be used together. Talk to your healthcare provider before taking metronidazole during Myleran treatment.
Mifepristone may increase the level of Myleran in your bloodstream, increasing your risk for Myleran side effects. This interaction is more likely to be a concern when mifepristone is taken on an ongoing basis, as opposed to a one-time mifepristone dose that is used to end an early pregnancy.
Phenytoin may decrease blood levels of Myleran, potentially decreasing its effectiveness. Your healthcare provider may choose to monitor you more closely if you take these medicines together.
Combining roflumilast with Myleran may further increase your risk for developing infections. Talk to your healthcare provider about this potential interaction before taking these medicines together.
Myleran may prevent sipuleucel-T from working like it should. This is because sipuleucel-T is thought to work by stimulating the body's immune system, while Myleran decreases the activity of the immune system. Talk to your healthcare provider about this possible interaction before using these medicines together.
Chemotherapy medicines, including Myleran, have been reported to both increase and decrease the effects of warfarin. Therefore, if you take warfarin during Myleran treatment, your healthcare provider may need to closely monitor your prothrombin time ("protime" or PT) and international normalized ratio (INR), and adjust your warfarin dose if needed.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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