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Morphine sulfate ER is a prescription medication used for the long-term treatment of pain. The drug comes in the form of extended-release capsules or tablets, and is typically taken once, twice, or three times daily. Because morphine sulfate ER is a narcotic, it has the potential for abuse and may not be suitable for someone who has a history of drug or alcohol abuse. Possible side effects include constipation, drowsiness, and nausea.

What Is Morphine Sulfate ER?

Morphine sulfate ER ("extended release") is the generic name for several long-acting prescription pain medications. These medications should only be used when around-the-clock use of strong painkillers is necessary for an extended period of time (for more than a few days). The brand names for the various different morphine sulfate ER products include:
(Click What Is Morphine Sulfate ER Used For? for more information, including possible off-label uses.)

Side Effects of Morphine Sulfate ER

As with any medicine, morphine sulfate ER can cause side effects. However, not everyone who takes the drug will experience side effects. Most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider. Serious side effects are less common.
Common side effects of morphine sulfate ER include, but are not limited to:
  • Constipation
  • Nausea and vomiting
  • Lightheadedness and dizziness
  • Drowsiness
  • Unusual, unpleasant feelings (dysphoria) or unusual, pleasant feelings (euphoria)
  • Sweating.
(Click Side Effects of Morphine Sulfate ER to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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