Cancer Home > Marinol Dosage

One of the primary factors that affect the recommended dose of Marinol is the condition being treated. For example, a person using this drug to relieve chemotherapy-induced nausea and vomiting will likely take Marinol more often than someone using it to treat AIDS-related anorexia and weight loss. The dosage will also be adjusted to ensure the drug's effectiveness while minimizing the risk of side effects.

An Introduction to Dosing With Marinol

The dose of Marinol® (dronabinol) your healthcare provider recommends will vary, depending on a number of factors, including:
  • The reason you are taking Marinol
  • Your height and weight
  • How you respond to the drug
  • Side effects you experience.
Your healthcare provider will adjust your dosage to give you the maximum benefit with the least likelihood of side effects. As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.

Marinol Dosage for AIDS-Associated Anorexia

People with AIDS often suffer from severe anorexia, or an inability to eat (this is different from anorexia nervosa, the well-known eating disorder), which results in weight loss. The standard initial Marinol dose for appetite stimulation in people with AIDS is 2.5 mg twice daily: before lunch and before dinner.
This amount may be reduced to 2.5 mg just once daily, at dinner or bedtime, in people who experience significant Marinol side effects. If higher doses are needed, the amount may be gradually increased to a maximum of 10 mg twice a day.

Marinol Dosage for Chemotherapy-Related Nausea and Vomiting

This medication may be given one to three hours before cancer chemotherapy and then every two to four hours after chemotherapy, for a total of four to six doses a day. Your healthcare provider will recommend a specific dosage of Marinol using your body surface area, which is usually calculated using your height and weight.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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