Cancer Home > Precautions and Warnings With Liposomal Vincristine

Before receiving liposomal vincristine, talk to your healthcare provider about your medical history, particularly if you have problems such as liver disease, difficulty walking, or joint pain. Other precautions and warnings associated with liposomal vincristine include potential drug interactions, nerve problems, and intestinal blockage. Risks also apply to women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to receiving liposomal vincristine sulfate (Marqibo®) if you have:
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Kidney disease, such as kidney failure (renal failure)
  • A disorder of the nerves, brain, or spinal cord, including a rare genetic condition known as Charcot-Marie-Tooth (CMT) syndrome
  • Numbness, tingling, pain, or burning sensations of your skin
  • Weakness of your hands or feet
  • Difficulty walking
  • Problems picking up and holding things with your hands
  • Decreased or increased sensitivity to touch, heat, cold, or pain in your hands or feet
  • Constipation
  • Problems urinating
  • Head, face, or jaw pain
  • Decreased reflexes
  • Abdominal (stomach) pain, swelling (distention), or fullness
  • Joint pain
  • Muscle pain, weakness, or spasms
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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