Cancer Home > Liposomal Vincristine

If you have a certain type of acute lymphoblastic leukemia, your healthcare provider may recommend treatment with liposomal vincristine. This medication is used when the cancer has come back or gotten worse after at least two other leukemia treatments have been tried. It is given once a week as an intravenous (IV) injection. Common side effects include nausea, fever, and constipation.

What Is Liposomal Vincristine?

Liposomal vincristine sulfate (Marqibo®) is a prescription medication approved to treat adults with a specific type of cancer of the blood and bone marrow known as Philadelphia chromosome negative (Ph-) acute lymphoblastic leukemia (ALL). The medication is approved for use in people whose cancer has returned or gotten worse after treatment with at least two other anti-leukemia therapies. 
(Click What Is Liposomal Vincristine Used For? for more information, including possible off-label uses.)

Are There Side Effects?

Just like other chemotherapy medication, liposomal vincristine can cause side effects, some of which can be significant. Although not everyone who uses the drug will have problems, most people will experience some type of liposomal vincristine side effect during treatment.
Common side effects of liposomal vincristine include but are not limited to:
(Click Liposomal Vincristine Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
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Last reviewed by: Kristi Monson, PharmD;
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