Cancer Home > Drug Interactions With the Histrelin Implant

When certain diabetes medications are used in combination with histrelin implants, there is a possibility for drug interactions. Some of these reactions can decrease the effectiveness of the diabetes medicines. Your healthcare provider may recommend that you check your blood glucose levels more often and may need to adjust your dosages of the diabetes medications.

An Overview of Histrelin Implant Interactions

The histrelin implant (Supprelin® LA, Vantas®) is a prescription hormone medication. This medication is not likely to react with most other drugs. However, interactions may occur when histrelin implants are combined with certain medicines used to treat diabetes, including:
  • Alpha-glucosidase inhibitors, such as:
  • Bromocriptine (Cycloset™)
  • Dipeptidyl peptidase-4 (DPP-4) inhibitors and combination DPP-4 medications, such as:
  • Glitazones and glitazone combination medications, such as:
  • Glucagon-like peptide 1 receptor agonists, such as:
  • Insulin of any type
  • Meglitinides, such as:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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