Cancer Home > Hecoria Side Effects

Common Side Effects

Hecoria is a generic version of Prograf®, a drug that has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking Prograf were carefully documented and compared to the reactions that occurred in a group of people taking a different anti-rejection medication. As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group taking the other medicine.
In these studies, the most commonly observed Prograf side effects included:
  • High blood pressure (hypertension) -- in up to 89 percent of people
  • Diarrhea -- up to 72 percent
  • Increased blood sugar levels -- up to 70 percent
  • Anemia (low red blood cell counts) -- up to 65 percent
  • Headache -- up to 64 percent
  • Insomnia -- up to 64 percent
  • Pain -- up to 63 percent
  • Abdominal (stomach) pain -- up to 59 percent
  • Tremors -- up to 56 percent
  • Kidney problems -- up to 56 percent
  • Weakness or low energy -- up to 52 percent.
Keep in mind that some of these percentages came from studies of Prograf for heart transplantation, which is not yet an approved use for Hecoria.
Other common side effects, occurring in 16 percent to 49 percent of people, included:
  • Low blood levels of phosphate
  • Low blood levels of magnesium
  • Fever
  • Nausea
  • Infection
  • Tingling, pricking, or numbing sensation of the skin
  • Swelling of the hands, legs, ankles, or feet
  • Constipation
  • Abnormal liver enzyme tests
  • Itching
  • Decreased appetite
  • Urinary tract infection (UTI, such as a bladder infection)
  • High or low levels of potassium in the blood
  • High blood lipids (increased cholesterol)
  • Breathing problems, including shortness of breath and coughing
  • Back pain
  • Vomiting
  • Heartburn or indigestion
  • Joint pain
  • Rash
  • Low platelet count
  • Dizziness
  • Chest pain
  • Swelling in the body (edema)
  • Less frequent urination
  • Low white blood cell counts (leukopenia).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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