Cancer Home > Precautions and Warnings With Fulvestrant

Precautions and warnings with fulvestrant to be aware of include potential drug interactions, the risk of taking it while pregnant or nursing, and the safety of taking the drug if you have not gone through menopause. Tell your healthcare provider if you have liver disease or a bleeding disorder before starting treatment. Precautions and warnings with fulvestrant include being aware of possible side effects.

Fulvestrant: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking fulvestrant (Faslodex®) if you have:
  • A bleeding disorder
  • Low levels of platelets in your blood (thrombocytopenia)
  • Liver disease, including liver failure or cirrhosis
  • Not gone through menopause
  • Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about all medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Fulvestrant

Some warnings and precautions to be aware of prior to taking fulvestrant include the following:
  • It is not known if fulvestrant is safe and effective for cancer treatment in premenopausal women, although it is sometimes prescribed in an off-label fashion for this use.
  • The liver helps clear fulvestrant from the body. Therefore, if you have liver disease, talk with your healthcare provider before taking it. Depending on the severity of your condition, your healthcare provider may suggest a different breast cancer treatment.
  • Fulvestrant may interact with other medications (see Drug Interactions With Fulvestrant).
  • Fulvestrant is a considered a pregnancy Category D medication. This means that it is likely to cause harm to a fetus during pregnancy. Talk to your healthcare provider about the risks and benefits of taking the drug while pregnant (see Faslodex and Pregnancy).
  • It is not known if fulvestrant passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Faslodex and Breastfeeding).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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