Cancer Home > Precautions and Warnings With Fludarabine

If you have a weakened immune system or severe bone marrow depression, talk to your healthcare provider about the warnings and precautions that may apply to you before beginning treatment with fludarabine. This chemotherapy treatment is not appropriate for some people, including those who are taking certain medications or who have certain allergies. Risks may also apply to women who are pregnant or nursing.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to receiving fludarabine phosphate (Fludara®) if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • Severe bone marrow depression (extremely low counts of white blood cells, red blood cells, or platelets)
  • A condition that causes a weakened immune system
  • A history of infections because your immune system was weak
  • Received previous chemotherapy or radiation treatment
  • Plans to receive a vaccination
  • Had an autoimmune reaction in which the immune system attacks the body's blood cells, such as:
    • Hemolytic anemia
    • Autoimmune thrombocytopenia
    • Evans syndrome
    • Acquired hemophilia
  • Plans to have surgery
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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