Cancer Home > Leukemia Chemotherapy Drug Fludarabine

A healthcare provider may prescribe a medication called fludarabine phosphate (Fludara®) to treat a certain type of cancer in adults. Specifically, this chemotherapy drug is approved to treat B-cell chronic lymphocytic leukemia when the cancer has not responded to (or has progressed despite) other treatment.
Fludarabine may also be prescribed for off-label (unapproved) reasons, such as treating acute myeloid leukemia and non-Hodgkin's lymphoma.
Fludarabine works to treat these forms of cancer by killing cancer cells. The medicine causes DNA damage, which interferes with the cells' ability to divide and multiply.
(Click What Is Fludarabine Used For? to learn more about using this chemotherapy drug for leukemia treatment. This article also offers an expanded list of off-label uses for the medication.)
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Last reviewed by: Kristi Monson, PharmD;
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