Cancer Home > Fludarabine and Fertility

Although fludarabine phosphate (Fludara®) can be an effective chemotherapy treatment, it may cause problems in some people. For instance, a person's fertility (the ability to have children) can be affected by fludarabine.
There have been reports of fludarabine damaging the testicles and sperm in males. This could cause infertility or increase the risk for birth defects. Men who have female partners of childbearing potential should use an effective form of birth control during and after treatment with fludarabine.
(To learn more, click Precautions and Warnings With Fludarabine. This resource discusses some of the other complications that may occur with this chemotherapy drug and explains what to talk to your healthcare provider about before beginning treatment).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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