Cancer Home > Cancer and Fludarabine

Adults who have a certain type of cancer may receive fludarabine phosphate (Fludara®). This drug is specially approved to treat B-cell chronic lymphocytic leukemia, a type of bone marrow and blood cell cancer. It is used when this cancer has not responded to other chemotherapy treatment, or has progressed after other chemotherapy treatment.
Fludarabine works by interfering with the way DNA replicates. Because cells need DNA to grow and divide, this medication can prevent the growth of cancer cells.
There are also some unapproved, or "off-label," uses for fludarabine, such as:
  • Treating acute myeloid leukemia
  • Treating non-Hodgkin 's lymphoma
  • Preparing the body for a bone marrow transplant. 
(Click What Is Fludarabine Used For? for more information on using fludarabine for cancer treatment. This article also offers detailed information on how this drug works and whether it is prescribed for children.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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