Cancer Home > Fentora

Fentora is approved for the treatment of pain. Specifically, this narcotic drug is used to treat breakthrough cancer pain in people who are taking regularly scheduled doses of another narcotic pain medication. It comes in the form of a tablet that is dissolved in the mouth, and is typically taken as needed. Possible side effects include dizziness, constipation, and nausea.

What Is Fentora?

Fentora® (fentanyl buccal tablets) is a prescription narcotic pain medication licensed to treat breakthrough pain (sudden flares of pain that "break through" around-the-clock pain medication). It is meant for use in people who have cancer and who are also taking regularly scheduled narcotic pain medication for their constant pain. Fentora is available as a small tablet, to be dissolved on the gums or under the tongue in the mouth.
This medication is a Schedule II controlled substance because it has a high potential for abuse and addiction. As a controlled substance, its use is highly regulated. Schedule II controlled substances are considered to have the highest abuse potential of all prescription medications.
(Click Fentora Uses for more information, including possible off-label uses.)

Who Makes This Medication?

Fentora is sold by Teva Pharmaceuticals USA, Inc.

How Does Fentora Work?

Fentora contains fentanyl, which is a very strong opioid narcotic medication. Fentanyl binds to the opioid mu-receptors throughout the body, producing many different effects. Some of these effects, such as pain relief, are desirable; other effects, such as slowing down the digestive tract, are undesirable and lead to side effects (such as constipation).
The effects of fentanyl include but are not limited to:
  • Pain relief
  • Drowsiness
  • Changes in mood, including feelings of unease (dysphoria) or unusually pleasant feelings (euphoria)
  • Cough suppression
  • Slowed or shallow breathing
  • Slowing of the digestive tract
  • Pupil constriction
  • Itching
  • Physical dependence.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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