Cancer Home > Etoposide Injection Dosage

Guidelines for dosing etoposide injection will largely depend on your height and weight. Other factors that may affect your dosage include the type of cancer you have and how well you tolerate the medicine. Etoposide injection is given slowly into a vein (intravenously). Each infusion takes about 30 to 60 minutes and will be administered by a healthcare provider.

An Introduction to Your Dosage of Etoposide Injection

The dose of etoposide injection (Toposar®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your height and weight
  • The type of cancer you have
  • How well you tolerate the medication
  • Other medications you are taking
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

What Is the Recommended Etoposide Injection Dosage for Small Cell Lung Cancer?

Like many chemotherapy medicines, etoposide injection dosing is based on body surface area, which is normally calculated using your height and weight. Doses based on body surface area are expressed as milligrams per meter squared (mg per m2).
The usual dosage of etoposide injection for treating small cell lung cancer is highly individualized, and may range from 35 mg per m2 a day for 4 days to 50 mg per m2 a day for 5 days. People with kidney or liver disease are normally given lower doses.
This medication can cause significant side effects, especially bone marrow depression (when the bone marrow is unable to produce adequate amounts of red blood cells, white blood cells, and platelets). After receiving etoposide injections for four to five days, you will be given a break in treatment to allow your body to recover from side effects. The "cycle" of four to five days of etoposide injections followed by a break will be repeated every three to four weeks, after you have recovered from potentially serious side effects. Your healthcare provider will tell you how many treatment cycles you need.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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