Cancer Home > Degarelix

Available by prescription only, degarelix is used to treat advanced prostate cancer in men. This medicine works by stopping production of testosterone in the testes, slowing down the growth of prostate cancer cells (which are dependent on testosterone to grow). This injection is given just under the skin of the abdomen (stomach) every 28 days. Hot flushes, fatigue, and weight gain are possible side effects.

What Is Degarelix?

Degarelix (Firmagon®) is a hormone therapy medication approved for the treatment of advanced prostate cancer. It belongs to a group of medications called gonadotropin-releasing hormone (GnRH) antagonists or blockers.
(Click What Is Degarelix Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, degarelix may cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Common side effects of degarelix include but are not limited to:
  • Fatigue
  • Hot flushes
  • Weight gain
  • Reactions at the injection site, such as redness, swelling, or pain.
(Click Degarelix Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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