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Children who have acute lymphoblastic leukemia (ALL) may benefit from treatment with clofarabine. This prescription drug is reserved for use after at least two other treatment regimens have been unsuccessful. It is given as an injection into a vein once a day for five days in a row, every two to six weeks. Your dosage will depend on your height and weight, among other factors.

 

What Is Clofarabine?

Clofarabine (Clolar®) is a prescription medication approved to treat children age 1 to 21 years old with acute lymphoblastic leukemia (ALL), a type of cancer of the blood and bone marrow. It is used after at least two other treatment regimens have failed. Clofarabine belongs to a group of medicines called purine analogs.
 
(Click What Is Clofarabine Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any chemotherapy medicine, clofarabine can cause side effects, some of which can be significant and potentially serious. Talk with your healthcare provider about ways to prevent or lessen reactions to this drug.
 
Possible side effects of clofarabine include but are not limited to:
 
  • Vomiting
  • Nausea
  • Diarrhea
  • Fever
  • Low blood cell counts (red blood cells, white blood cells, and platelets).
 
(Click Clofarabine Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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