Cancer Home > Clofarabine Side Effects

Some of the possible side effects of clofarabine can include headaches, itching, and nausea. Studies have shown that most people who use this drug will develop some type of reaction. Because clofarabine is associated with potentially serious reactions, such as dangerous infections and bleeding problems, let your healthcare provider know immediately if you develop something that doesn't seem right.


An Introduction to Side Effects of Clofarabine

As with any chemotherapy medicine, clofarabine (Clolar®) can cause side effects. In fact, most people will experience some type of reaction to this drug, and some problems can be quite significant. Talk to your healthcare provider about ways to prevent or lessen reactions to this medicine.
(This article covers many, but not all, of the possible side effects with clofarabine. Your healthcare provider can discuss a more complete list with you.)

Serious Clofarabine Side Effects

Some side effects of clofarabine are potentially serious and should be reported to your healthcare provider right away. These reactions include but are not limited to:
  • Signs of anemia, such as:
    • Unusual tiredness
    • Weakness
    • Pale skin
    • Shortness of breath
  • Unusual bleeding or bruising
  • Black, tarry, or bloody stools
  • Blood in the urine
  • Nosebleeds
  • Bleeding gums
  • Small red or purple spots under the skin
  • Fast breathing, difficulty breathing, or shortness of breath
  • A fast heartbeat
  • Lightheadedness, dizziness, or fainting
  • Tingling, redness, dryness, or flaking of the hands or feet
  • Anxiety, nervousness, or irritability
  • Yellowing of the skin or whites of the eyes (jaundice)
  • A change in how much or how often you urinate
  • Swelling or sores on the inside of the mouth or throat
  • White patches inside the mouth
  • Severe or persistent nausea, vomiting, or diarrhea
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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