Cancer Home > Chlorambucil

People who have lymphoma or chronic lymphocytic leukemia may benefit from chlorambucil. This prescription medicine works by disrupting the multiplication process of the cancer cells. Although this medication is not a cure, it can help minimize symptoms. Side effects may include diarrhea, nausea, and vomiting. This product comes as a tablet and is taken once daily on an empty stomach.

What Is Chlorambucil?

Chlorambucil (Leukeran®) is a prescription chemotherapy medication approved to treat certain cancers of the blood cells, including chronic lymphocytic leukemia and lymphoma. Although it is not a cure for these cancers, chlorambucil may help reduce symptoms.
(Click What Is Chlorambucil Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, chlorambucil can cause side effects. As with other chemotherapy medicines, the side effects can be significant and potentially serious. Talk with your healthcare provider about ways to prevent or lessen reactions to this drug.
Common side effects of chlorambucil include but are not limited to:
  • Low white blood cells
  • Low red blood cells (anemia)
  • Low platelets
  • Nausea and vomiting
  • Diarrhea.
(Click Chlorambucil Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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