Cancer Home > Leukemia Chemotherapy Drug Bendamustine

As a type of chemotherapy drug, bendamustine (Treanda®) is prescribed to treat chronic lymphocytic leukemia (CLL) and certain types of lymphoma. It comes as an injection that is given slowly into a vein (an intravenous, IV, infusion). It is administered by a healthcare provider in a healthcare setting for two days in a row, every 21 to 28 days.
 
CLL is a slow-growing leukemia that starts in the lymphocytes (a type of blood cell). Leukemia occurs when the bone marrow produces a large amount of abnormal blood cells that grow out of control. These abnormal blood cells eventually crowd out normal, healthy blood cells. This can lead to serious problems, including bleeding, anemia, and infection.
 
When used as a chemotherapy treatment for this type of leukemia, bendamustine works by interfering with DNA replication, which is a process necessary for cells to copy themselves and divide. This causes cell death.
 
(Click What Is Bendamustine Used For? for a closer look at this chemotherapy drug, including an explanation on how the drug works to treat leukemia and lymphoma.)
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Last reviewed by: Kristi Monson, PharmD;
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