Cancer Home > Precautions and Warnings With Axitinib
If you have a history of a heart attack, stroke, or bleeding problems, talk to your healthcare provider about whether you can safely use axitinib. This chemotherapy medication can cause potentially dangerous complications for some people, including those with certain allergies or people taking certain medications. Other warnings and safety precautions for axitinib apply to women who are pregnant or breastfeeding.
What Should I Tell My Healthcare Provider?You should talk with your healthcare provider prior to taking axitinib (Inlyta®) if you have:
- Liver disease, such as hepatitis, cirrhosis, or liver failure
- Kidney disease, such as kidney failure (renal failure)
- High blood pressure (hypertension)
- A history of blood clots
- Had a heart attack, stroke, or transient ischemic attack (TIA or "mini-stroke")
- An untreated brain tumor
- A history of bleeding problems, such as bleeding in your stomach, intestines, or brain
- Thyroid problems, such as an underactive or overactive thyroid (hypothyroidism or hyperthyroidism)
- Wounds that have not healed
- Plans to have surgery
- A tear in your stomach or intestines (a perforation) or an abnormal connection between two parts of your gastrointestinal (GI) tract (a fistula)
- Experienced a neurological condition known as reversible posterior leukoencephalopathy syndrome
- Been told you have abnormal amounts of protein in your urine
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Inlyta and Pregnancy)
- Breastfeeding (see Inlyta and Breastfeeding).
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.