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The recommended Anzemet dosage for the prevention of nausea and vomiting caused by chemotherapy is 100 mg, taken an hour before the start of chemotherapy. To help prevent nausea and vomiting due to surgery, Anzemet is given by IV about 15 minutes before the end of anesthesia. Anzemet dosing for children ages 2 to 16 is generally based on the child's body weight.

Anzemet Dosage: An Introduction

The dose of Anzemet® (dolasetron mesylate) that your healthcare provider recommends will vary depending on a number of factors, including:
 
  • Your age and weight
  • Whether you are having surgery or chemotherapy
  • Other medications you may be taking
  • Other medical conditions you may have.
     
As is always the case, do not adjust your Anzemet dose unless your healthcare provider specifically instructs you to do so.
 

Anzemet Dosing for Surgery

For preventing nausea and vomiting due to surgery, Anzemet is given by IV about 15 minutes before the end of anesthesia. If it isn't given during surgery, a dose can be given at any time after surgery if nausea or vomiting develop.
 
For this use, the recommended adult Anzemet dosage is 12.5 mg given intravenously (by IV).
 
For children ages 2 to 16, the recommended dose is based on weight -- Anzemet 0.35 mg per kg of body weight (about 0.16 mg per pound).
 
Anzemet tablets are not approved for this use.
 

Anzemet Dosing for Chemotherapy

For adults, the recommended Anzemet dose for the prevention of nausea and vomiting due to chemotherapy is 100 mg taken by mouth within one hour before chemotherapy. For children ages 2 to 16, the recommended dose is based on weight -- Anzemet 1.8 mg per kg of body weight (about 0.8 mg per pound) taken by mouth within one hour before chemotherapy.
 
The injectable form of Anzemet is not approved for this use. 
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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