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In studies on Aloxi and pregnancy, the drug did not cause any problems when it was given to pregnant rats and rabbits. Since animals do not always respond to medicines the same way that humans do, however, Aloxi can be prescribed if the benefits outweigh the risks to the unborn child. If you are taking Aloxi and pregnancy occurs, notify your healthcare provider right away.

Can I Take Aloxi When Pregnant?

Aloxi® (palonosetron hydrochloride) is a prescription nausea and vomiting medication. It is approved to be used to prevent nausea and vomiting due to chemotherapy or surgery. While Aloxi appears to be safe for these temporary or short-term uses during pregnancy; it is not approved to treat morning sickness.
 

Aloxi and Pregnancy Category B

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category B is given to medicines that have not been studied in pregnant humans but that do not appear to cause harm to the fetus in animal studies.
 
Aloxi has been studied at high doses in pregnant rats and rabbits without causing any problems. However, it is important to note that animals do not always respond to medicines the same way that humans do. Therefore, a pregnancy Category B medicine should be given to a pregnant woman only if her healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child.
 
Aloxi should not be used to treat nausea and vomiting that is associated with pregnancy (morning sickness). The drug has never been studied for long-term use. It is not known if Aloxi has any long-term side effects, and it not known if it is safe when used long-term.
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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