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Side Effects of Letrozole

When side effects of letrozole occur, they are usually minor and easily treated. Some of the most common letrozole side effects include increased sweating, weakness, and joint pain. However, a number of side effects with letrozole are more serious and should be reported immediately to a healthcare provider. Among these serious side effects are signs of a blood clot and an increase in tumor size or the appearance of new tumors.

An Introduction to Side Effects of Letrozole

As with any medicine, side effects are possible with letrozole (Femara®); however, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. When side effects do occur, in most cases they are minor and either require no treatment or are easily treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with letrozole. Your healthcare provider can discuss a more complete list of letrozole side effects with you.)
 

Common Side Effects of Letrozole

Letrozole has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people taking the drug are documented and are then compared to side effects that occur in another group of people not taking the medicine. In these studies, the most common side effects of letrozole included:
 
Some other common side effects (occurring in 2 percent to 15 percent of people) included:
 
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Letrozole Drug Information

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