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Side Effects of Letrozole

Serious Side Effects of Letrozole

Some side effects with letrozole, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
  • An increase in tumor size or the appearance of new tumors
     
  • Difficulty breathing
     
  • Unusual or unexplained vaginal bleeding
     
  • Chest pain
     
  • Signs of a blood clot, such as:
     
    • Pain
    • Swelling
    • Tenderness (especially in the legs)
 
  • Signs of an allergic reaction, including:
     
    • Unexplained rash
    • Hives
    • Itching
    • Unexplained swelling.
 

Final Thoughts on Side Effects of Letrozole

You may experience some or none of the letrozole side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking the drug. You should also let your healthcare provider know if you develop something that "just does not seem right" during treatment with letrozole. While it may not be a letrozole side effect, your healthcare provider will be able to diagnose and treat the problem.
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Letrozole Drug Information

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