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Lazanda and Breastfeeding

The manufacturer of Lazanda (fentanyl nasal spray) recommends that women avoid using this medication while breastfeeding. Although the drug has not been adequately studied in nursing women, it is known that the active ingredient in the drug does pass through breast milk in small amounts. This may cause potentially serious problems in the infant, such as poor feeding or difficulty breathing.

Can Breastfeeding Women Use Lazanda?

Lazanda® (fentanyl nasal spray) is a prescription medication approved for breakthrough pain in adults with cancer. Lazanda contains fentanyl, a strong narcotic pain medication. This drug is known to pass through breast milk, and the manufacturer recommends that women avoid using Lazanda while nursing.
If you are breastfeeding or thinking about breastfeeding, you should talk to your healthcare provider before using Lazanda.

More Information on Lazanda and Breastfeeding

Lazanda has not been adequately studied in breastfeeding women. Fentanyl, the active ingredient in Lazanda, is known to pass through breast milk in small amounts. While the amount of fentanyl passed through is thought to be small, most studies have looked at single fentanyl doses. There is very little information available about the effects of repeated fentanyl doses, which would be the case with Lazanda use.
Infants exposed to fentanyl in breast milk may experience unusual drowsiness, difficulty feeding (which could lead to problems gaining weight), or breathing problems.
In addition, if you have been using Lazanda while breastfeeding, and stop using the medicine or stop breastfeeding, watch for potential withdrawal symptoms in your child. Withdrawal symptoms may include but are not limited to:
  • Changes in behavior, such as irritability, jitteriness, or restlessness
  • Excessive or high-pitched crying
  • Poor feeding
  • Increased muscle tone
  • Fever
  • Diarrhea
  • Seizures.
If you notice any of these problems, or if something "just does not seem right," immediately contact your healthcare provider.
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