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Kytril Warnings and Precautions

To help ensure safe treatment with Kytril, warnings and precautions for the drug should be discussed ahead of time with your healthcare provider. Be sure to let your healthcare provider know if you have liver disease or any allergies before taking Kytril. You should avoid taking Kytril altogether if you are allergic to any active or inactive ingredients used to make the medicine.

What Should I Tell My Healthcare Provider Before Taking Kytril?

You should talk with your healthcare provider prior to taking Kytril® (granisetron hydrochloride) if you have:


Also, let your healthcare provider know if you:
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding.
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Kytril

Warnings and precautions to be aware of prior to taking Kytril include the following:
  • Kytril can interact with a few other medications (see Kytril Drug Interactions for more information).
  • If you have liver disease, your body may not metabolize Kytril as well as it should. Therefore, you may require extra monitoring by your healthcare provider and you may need to take a lower Kytril dosage. However, most people with liver problems do not need a lower Kytril dosage.


  • There have been reports of a certain change in heart rhythm (known as QT prolongation) in people taking Kytril. This heart rhythm change can be dangerous. People with heart disease or an electrolyte imbalance may be at a higher risk for this problem. Taking Kytril with certain other medications may also increase this risk (see Kytril Drug Interactions)


  • Kytril is considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are not known (see Kytril and Pregnancy).
  • It is not known if Kytril passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Kytril and Breastfeeding).
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Kytril Drug Information

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