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Kyprolis and Breastfeeding

It is unclear if Kyprolis (carfilzomib) passes through breast milk. However, women are generally advised to not breastfeed during treatment, as this drug is associated with potentially serious risks like bleeding, anemia, and infections. Before using Kyprolis while breastfeeding, discuss the potential risks and benefits with your healthcare provider.


Can Breastfeeding Women Use Kyprolis?

Kyprolis™ (carfilzomib) is a prescription chemotherapy medication used to treat adults with multiple myeloma, a type of blood cancer. At this time, it is unknown if Kyprolis passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider before beginning treatment.

More Information on Kyprolis and Breastfeeding

Kyprolis has not been studied in breastfeeding women. Therefore, it is unknown if the drug passes through breast milk, or if it would harm a nursing child. Although this lack of information is certainly frustrating, it is important to understand that most medicines are not studied in breastfeeding women, as doing so could expose an infant, who will not directly benefit from the medication, to possible harm.
Kyprolis is associated with potentially serious side effects, including anemia, bleeding, and an increased risk for infections. Because many medicines are passed through breast milk, and because of the potential for serious side effects in a nursing child, the manufacturer of Kyprolis recommends that women not breastfeed during treatment. If you are interested in breastfeeding after treatment, talk to your healthcare provider about when it may be safe to do so.

Talking With Your Healthcare Provider

You should discuss breastfeeding and Kyprolis use with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.
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