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Ipilimumab Side Effects

Some of the most commonly reported side effects of ipilimumab include a rash, fatigue, and diarrhea. While reactions such as these are typically minor, there are some potentially serious complications that require immediate medical treatment. For example, contact your healthcare provider right away if you develop bloody stools, yellowing of the skin or whites of the eyes, or other potentially serious reactions.

An Introduction to Side Effects of Ipilimumab

Just like any medicine, ipilimumab (Yervoy™) can cause side effects. However, not everyone who receives the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with ipilimumab. Your healthcare provider can discuss a more complete list with you.)

Serious Ipilimumab Side Effects

Some side effects of ipilimumab are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Severe diarrhea
  • Black, tarry, or bloody stools
  • Abdominal (stomach) pain or bloating
  • Signs of liver problems, such as:
    • Yellowing of the skin or whites of the eyes (jaundice)
    • Dark urine
    • Tiredness or fatigue
    • Pain in the upper-right area of the abdomen (stomach)
  • Redness, blistering, or peeling of the skin
  • Sores in the mouth
  • Numbness, tingling, or weakness of the legs, arms, hands, or feet
  • Extreme tiredness, feeling cold all the time, or weight gain
  • Changes in mood
  • Feeling dizzy or faint
  • Eye or vision problems, such as:
    • Blurred vision
    • Double vision
    • Eye pain
    • Eye redness.
Some ipilimumab side effects have been reported months after treatment ended. Therefore, make sure to tell your healthcare provider about potentially serious side effects that you may experience both during treatment and for several months after you stop receiving ipilimumab.
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