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Ifosfamide Side Effects

It is possible and fairly common to develop side effects while using ifosfamide. Clinical studies showed that blood in the urine, anemia, and hair loss were common reactions. Although these problems are common, they may also be potentially serious and require medical care. Contact your healthcare provider right away if you experience things like fever, unusual bleeding, or unexplained weight gain.

An Introduction to Side Effects of Ifosfamide

As with any chemotherapy medicine, ifosfamide (Ifex®) can cause side effects. In fact, most people will experience some type of reaction to this drug, and some side effects can be quite significant. Talk to your healthcare provider about ways to prevent or lessen reactions to this medicine.
 
(This article covers many, but not all, of the possible side effects with ifosfamide. Your healthcare provider can discuss a more complete list with you.)
 

Serious Ifosfamide Side Effects

Some side effects of ifosfamide are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
  • Signs of an infection, such as:
 
    • Fever
    • Chills
    • Aches and pains
    • Sore throat
    • Painful urination
 
  • Signs of anemia, such as:
 
    • Extreme weakness or fatigue
    • Pale skin
    • Shortness of breath
    • Dizziness
 
  • Any unusual bleeding or bruising
  • Black, tarry, or bloody stools
  • Blood in the urine, with or without painful urination
  • Loss of bladder control (incontinence)
  • Confusion
  • Changes in mood or behavior
  • Hallucinations or delusions (see, hearing, or believing things that are not true)
  • Changes in vision, such as blurred vision or a reduced ability to see clearly
  • Reduced hearing
  • Ringing in the ears
  • Seizures
  • Muscle stiffness, spasms, twitches, or tremors
  • Mouth or throat sores, ulcers, or blisters
  • Dizziness or fainting
  • Signs of liver problems, such as:
 
    • Dark urine
    • Loss of appetite
    • Fatigue or excessive tiredness
    • Upper-right abdominal (stomach) pain
    • Yellowing of the whites of the eyes or skin (jaundice)
 
  • Swelling of the arms, hands, legs, ankles, or feet
  • Unexplained weight gain
  • A fast or otherwise abnormal heartbeat
  • Swelling, burning, stinging, pain, or leakage of fluid around your infusion site (the site where you receive your dose)
  • Persistent or severe nausea and vomiting
  • Wounds that do not heal or are slow to heal
  • Signs of an allergic reaction, such as:
 
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
 
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Ifosfamide Drug Information

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