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Ifosfamide Dosage

Ifosfamide comes as an intravenous infusion and is used to treat testicular cancer. It is administered by a healthcare provider usually once a day for five days every three weeks. Your particular dosage of ifosfamide, however, will depend primarily on your height and weight, as well as how you tolerate the medicine and other medical conditions you may have.

An Introduction to Your Dosage of Ifosfamide

The dose of ifosfamide (Ifex®) your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your height and weight
  • How you tolerate the medication
  • Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Recommended Ifosfamide Dosing Guidelines

Like many chemotherapy medicines, the ifosfamide dose your healthcare provider recommends will be based on your body surface area. Body surface area is calculated using your height and weight. Doses based on body surface area are expressed as milligrams (mg) or grams (g) per meter squared (m2).
The usual recommended dosage of ifosfamide for treating testicular cancer is 1.2 g per m2 once a day for five days in a row. This amount is repeated every three weeks. The break in treatment allows your blood cell counts to recover, as ifosfamide can cause bone marrow suppression (when the bone marrow does not make adequate amounts of blood cells). If your blood cell counts are too low when it is time for your next dose, your healthcare provider may recommend a longer break.
People with liver disease and kidney disease may need lower doses. Your healthcare provider will consider your liver and kidney function when recommending your specific amount.
Ifosfamide can be toxic to the bladder, and may cause hemorrhagic cystitis, a condition associated with bladder irritation and blood in the urine. In order to reduce the risk for this condition, ifosfamide is given in combination with a medication known as mesna (Mesnex®). Mesna can be given as an intravenous (IV) injection or as a tablet.
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Ifosfamide Drug Information

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