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Drug Interactions With Hydromorphone ER

Drug Interactions With Hydromorphone ER Explained

The following sections explain in detail the potentially negative interactions that can occur when hydromorphone ER is combined with any of the drugs listed above.
 
Alcoholic Beverages
You should avoid alcohol while taking hydromorphone ER. Alcohol increases the risk of serious side effects, such as extreme drowsiness, confusion, memory loss, or difficulty breathing.
 
Alvimopan
Hydromorphone ER may increase the risk of serious alvimopan side effects. Check with your healthcare provider before taking alvimopan if you have taken hydromorphone ER in the past seven days.
 
Antidepressants
Combining an antidepressant with hydromorphone ER could increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious problems may also occur. Talk to your healthcare provider before taking these drugs together, as you may need to be monitored more closely and the dose of your medications may need to be adjusted.
 
Antihistamines
Many antihistamines cause significant drowsiness and can cause serious problems when used in combination with other medications that cause drowsiness, such as hydromorphone ER. Check with your healthcare provider before taking hydromorphone ER with an antihistamine, including nonprescription ones.
 
Antipsychotics
Combining an antipsychotic medication with hydromorphone ER can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious problems may also occur. Talk to your healthcare provider before taking these products together.
 
Barbiturates
Combining a barbiturate with hydromorphone ER can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious problems may also occur. Talk to your healthcare provider before taking hydromorphone ER with a barbiturate.
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