Histrelin Implant

The histrelin implant is prescribed to treat advanced prostate cancer in men and central precocious puberty in children. This medicine works by stopping production of testosterone in the testes and estrogen production in the ovaries. This implant is surgically placed just under the skin of the upper arm, and provides continuous medication for 12 months. Side effects may include hot flushes, pain, and fatigue.

What Is the Histrelin Implant?

The histrelin implant (Supprelin® LA, Vantas®) is a prescription hormone medication that is inserted just beneath the skin, where it continuously releases medicine into the body for an entire year. It is approved to treat advanced prostate cancer in men (Vantas) and early onset puberty (known medically as central precocious puberty) in children (Supprelin LA).
 
(Click What Are Histrelin Implants Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any medicine, a histrelin implant may cause side effects.
 However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
 
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
 
Common side effects of the histrelin implant include but are not limited to:
 
  • Hot flushes
  • Reactions at the implant site
  • Fatigue
  • Pain.
 
(Click Histrelin Implant Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
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Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD
 
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