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Gliadel Wafers

Gliadel® (carmustine implant) is a type of chemotherapy treatment used for certain types of brain tumors. It comes as small, dime-sized wafers that are surgically implanted into the brain. Gliadel wafers are placed into the space that remains after a brain tumor is surgically removed.
 
Up to eight wafers can be used during each surgery to cover as much of the cavity as possible. The wafers can overlap slightly. They can also be broken in half, but should not be broken into more than two pieces.
 
After the wafers are in place, they begin to dissolve and release the active ingredient directly into the area. They work to help prevent the growth and multiplication of cancer cells by disrupting the replication process of DNA.
 
(To learn more about these wafers, click Gliadel. This full-length article discusses dosing guidelines for this chemotherapy drug, including details on how your dosage is determined and helpful tips on what to expect during treatment.)
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