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Gliadel Drug Interactions

Gliadel Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that could occur when Gliadel is combined with any of the drugs listed above.
Amphotericin B
Taking amphotericin B with chemotherapy medicines, such as Gliadel, has been reported to increase the risk for amphotericin B side effects, such as kidney damage, low blood pressure (hypotension), and breathing problems. Your healthcare provider may choose to monitor you more closely for these side effects if you use these medicines together.
Biologic and Immunologic Medications
Using Gliadel in combination with biologic and immunologic medications that suppress the immune system could increase your risk for potentially serious side effects, including low blood cell counts and infections. Talk to your healthcare provider about this potential interaction if you are taking biologic or immunologic medicines.
Using clozapine and Gliadel together may increase the risk for dangerously low white blood cell counts, which could make you susceptible to potentially serious infections. Talk to your healthcare provider before using these medicines together. However, do not stop taking clozapine unless your healthcare provider specifically tells you to do so.
Live Vaccinations
In general, people receiving chemotherapy, such as Gliadel, are advised to not receive live vaccines. Live vaccines contain live viruses or bacteria. Because you are more susceptible to infections during chemotherapy, you could become infected with the virus or bacteria used to make the vaccine. Also, live vaccines may be less effective in people who are undergoing chemotherapy treatment. Talk to your healthcare provider before getting a vaccination if you have received Gliadel.
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