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Gliadel and Breastfeeding

Because Gliadel (carmustine implant) is inserted directly into the brain, it is unknown how much of the medication, if any, would be absorbed into the bloodstream. Therefore, it is unclear how much might reach the breast milk or if it would pass through breast milk. However, this medicine is associated with serious problems, so the manufacturer recommends women not breastfeed during Gliadel treatment.

Can Breastfeeding Women Receive Gliadel?

At this time, it is unknown if Gliadel® (carmustine implant) passes through breast milk in humans. The manufacturer recommends that women treated with Gliadel not breastfeed. Therefore, if you are currently nursing a child, talk to your healthcare provider before receiving this medication.

More Information About Gliadel and Breastfeeding

Gliadel has not been studied in breastfeeding women. Therefore, it is unknown if the medication passes through breast milk, or if it would potentially harm a nursing child.
Carmustine, the active ingredient in Gliadel, has not been studied in breastfeeding women, but is expected to pass through breast milk based on its properties. Gliadel, however, is a little different from other forms of carmustine, as it is implanted directly into the brain. At this time, it is unknown how much, if any, would be found in the bloodstream, where it could pass through breast milk.
While the lack of information about breastfeeding and Gliadel is certainly frustrating, studies of medications are rarely done in breastfeeding women, as doing so would usually expose an infant, who will not directly benefit from the medication, to possible risks from the medication.
Because so little is known about Gliadel and breastfeeding, and because the medicine is associated with potentially serious side effects, it is probably best for a woman who receives this drug to not breastfeed.
If you have received Gliadel in the past and wish to breastfeed, talk to your healthcare provider. He or she can give you an idea of how long you should wait after receiving the implant before you are able to safely breastfeed.
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