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Fentora Drug Interactions

CYP 3A4 Inhibitor Medications
The body breaks down Fentora using enzymes in the liver known as CYP 3A4 enzymes. Some other medications (known as CYP 3A4 inhibitors) can decrease the activity of these enzymes. Combining Fentora with one of these CYP 3A4 inhibitors may increase the level of Fentora in your body, increasing your risk for serious side effects, including drowsiness, confusion, and breathing difficulty. Your healthcare provider may monitor you more closely for side effects if you take Fentora with a CYP 3A4 inhibitor.
Fentora can increase the risk for desmopressin side effects. Do not take Fentora with desmopressin without first speaking with your healthcare provider.
Grapefruit Juice
Grapefruit juice may increase the amount of Fentora in your blood, potentially increasing your risk for serious side effects, such as drowsiness, confusion, and breathing problems. Talk to your healthcare provider before eating grapefruit or drinking grapefruit juice while you are using Fentora.
Medications That Cause Drowsiness
Fentora causes significant drowsiness. Taking other medications that cause drowsiness while using Fentora may lead to serious side effects, such as extreme sedation, confusion, and serious breathing problems. Check with your healthcare provider before taking Fentora with other medications that can cause drowsiness.
Monoamine Oxidase Inhibitors (MAOIs)
Combining Fentora with an MAOI may potentially cause a serious reaction known as serotonin syndrome. It can also lead to low blood pressure. Do not use Fentora if you have taken an MAOI within the past 14 days.
Combining octreotide with Fentora may increase the pain-relieving effects of Fentora. Your healthcare provider may monitor your pain response if you take these medications together. You might need a lower Fentora dose.
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