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Drug Interactions With Fentanyl Sublingual Spray

Octreotide
Combining octreotide with fentanyl sublingual spray may increase the pain-relieving effects of fentanyl sublingual spray. Your healthcare provider may monitor your pain response if you take these medications together. You could need a lower fentanyl sublingual spray dose.
 
Pegvisomant
Fentanyl sublingual spray may decrease the effectiveness of pegvisomant. If you use these medications together, your healthcare provider may need to increase your pegvisomant dose.
 
Thiazide Diuretics
Using fentanyl sublingual spray with a thiazide diuretic may increase your risk for orthostatic hypotension (a decrease in blood pressure when you stand up). If you take these medications together, let your healthcare provider know if you experience any symptoms of orthostatic hypotension, such as faintness, dizziness, and lightheadedness.
 

Final Thoughts

It is possible that not all fentanyl sublingual spray drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about specific interactions that may apply to you.
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Fentanyl Sublingual Spray Information

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