Exemestane Dosing

For postmenopausal women who are treating breast cancer with exemestane, dosing typically starts at 25 mg once daily after a meal. Generally, women with early breast cancer can take exemestane after two to three years of taking tamoxifen. Some women who are taking certain other medications may need to take a higher dose of exemestane (50 mg once daily). Do not adjust your exemestane dose unless your healthcare provider specifically instructs you to do so.

 

Exemestane Dosing: An Introduction

The dose of exemestane (Aromasin®) that your healthcare provider recommends will vary, depending on a number of factors, including:
 
As is always the case, do not adjust your exemestane dose unless your healthcare provider specifically instructs you to do so.
 
Exemestane Dosing for Breast Cancer
The recommended dose of exemestane in postmenopausal women is exemestane 25 mg once daily after a meal. For women with early breast cancer, exemestane is approved for use after two to three years of tamoxifen (Nolvadex®, Soltamox®) for two to three additional years (for a total of five years of treatment). For women with more advanced breast cancer, exemestane should be continued until the breast cancer worsens.
 
Women taking certain other medications may need to take a higher dose -- exemestane 50 mg once daily after a meal (see Drug Interactions With Exemestane).
 

General Exemestane Dosing Information

Considerations for people taking exemestane include the following:
 
  • Exemestane comes in tablet form and is taken by mouth once a day.
     
  • Exemestane should be taken after a meal.
     
  • Exemestane should be taken at the same time each day to maintain an even level of the drug in your blood.
     
  • For the medication to work properly, it must be taken as prescribed. Exemestane will not work if you stop taking it.
     
  • If you are unsure about anything related to exemestane or your exemestane dosage, talk to your doctor, nurse, or pharmacist. Do not stop taking the drug without discussing it with your healthcare provider.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;