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Drug Interactions With Exemestane

A few of the medicines that can potentially cause drug interactions with exemestane include certain anticonvulsants, estrogens, and oral contraceptives. These exemestane drug interactions can decrease the level of exemestane in your blood, potentially making exemestane less effective. Therefore, you should be sure to talk with your pharmacist or healthcare provider about exemestane interactions that may apply to you.

An Overview of Drug Interactions With Exemestane

Exemestane (Aromasin®) can potentially interact with other medications. Some of these medicines that may lead to exemestane drug interactions include:
  • Certain anticonvulsants, including:
o Carbamazepine (Epitol®, Equetro™, Tegretol®, Tegretol® XR)
o Fosphenytoin (Cerebyx®)
o Phenobarbital (Luminal®)
o Pentobarbital (Nembutal®)

Exemestane Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when exemestane is combined with any of the drugs listed above.
Certain Anticonvulsants
Taking exemestane with certain anticonvulsants may decrease the level of exemestane in your blood, perhaps decreasing its effectiveness. Your healthcare provider may need to increase your exemestane dosage.
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Exemestane (Aromasin)

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